Cyndi's List - Hispanic, Central and South America, and the West Indies
More than 54,250 links with 43,400 links, categorized and cross-referenced, in over 100 categories. Another 10,800+ uncategorized new links in the works.

Hispanic Genealogy
The Institute of Genealogy and History for Latin America.

Shadcat's Free Genealogy Listings - Central / South America
Free research site which includes Central and South American resources.